Alex2

The ALEX 2 Test is an advanced laboratory assay used in the molecular diagnostics of IgE-mediated allergies. It is performed to identify both food and inhalant allergies. The test enables simultaneous measurement of total IgE as well as specific IgE antibodies for 295 allergens. It involves a venous blood draw, does not require special preparation, and results are available within 14 business days.

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What does the ALEX 2 Test involve?

The ALEX 2 Test is an advanced diagnostic assay used to identify IgE-mediated allergies. The package includes:

Total IgE, which determines the overall level of IgE antibodies regardless of their specificity (therefore it does not identify the source of allergy);
Specific IgE, measuring IgE antibody levels that increase in response to specific allergens.
The test involves a laboratory blood draw and sample analysis. A small venous blood sample is required at a designated collection point. The test is intended for both children and adults.

When should the ALEX 2 Test be performed?

The ALEX 2 Test is particularly useful when previous diagnostic tests have not provided clear results in allergy diagnosis, as well as in the following situations:

Identification of cross-reactivities – distinguishing primary sensitization from cross-reactive responses, which is especially important for patients allergic to multiple allergens;
Assessment of anaphylaxis risk – particularly recommended for individuals with food allergies to evaluate the risk of severe allergic reactions such as anaphylaxis;
Selection of immunotherapy – helps physicians choose appropriate allergen immunotherapy (desensitization) for patients with inhalant allergies and Hymenoptera venom allergies;
Monitoring tolerance development – may help determine the likelihood of developing tolerance to allergens, especially in children;
Management of coexisting conditions – patients treated in gastroenterology, pulmonology, or pediatrics may benefit from this test to better understand their allergic symptoms.

What does the ALEX 2 Test diagnose?

The ALEX 2 Test enables simultaneous diagnostics for 295 different allergens, including 178 molecular components and 117 extracts. The test is particularly useful in diagnosing food and inhalant allergies, allowing for the creation of a detailed individual allergy profile.